Drop In Bestsellers

Enough: Your Health, Your Weight, and What It's Like To Be Free

By Ania M. Jastreboff

Hardcover: pr8329397

Pub Date: Jan 2026

 

Throughout her adult life, Oprah Winfrey struggled with her weight. She never imagined, in her lifetime, that medication would bring hope, health, and a cure to people like her. But as her conversations with Dr. Ania Jastreboff of Yale School of Medicine reveal, we've learned that obesity isn't a choice. It's not a matter of willpower.

Obesity is a disease.

It's a matter of biology, created by our bodies' need for survival and the environment we've created and now live in.

And it is treatable.

New medications can lower our body fat set point (our brain's "enough" point), so we lose weight without fighting biology with willpower. Dr. Jastreboff outlines strategies for optimizing health and managing side effects with the reassuring perspective of decades of experience treating obesity patients and conducting studies with these medications.

Many of her patients say the noise of food that tormented them for years has evaporated. They describe a newfound freedom from intrusive, persistent, and disruptive thoughts about food. With the treatment, they begin a compassionate healing journey, free from the shame and blame they have endured from society for decades.

Oprah says she has learned so much from Dr. Jastreboff about how our bodies work with us and also against us. How each of our struggles is different, and each of our choices for living with obesity can also be different.

Dr. Jastreboff's groundbreaking research offers a new path forward, not only for treating obesity but for overall health, with important implications for preventing and reversing hundreds of related diseases. As she demonstrates in this book, when science meets empathy, true healing becomes possible.

Yes, there is a path to healing and living the life you've always wanted, when your brain is reassured that you've had enough.

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